The elimination of infectious disease has been a goal within reach of researchers since the global eradication of smallpox was officially endorsed by the World Health Assembly in 1980. Now, the immunization schedule for newborns provides protection against up to 14 infections, effectively eliminating some of these pathogens from countries with these programs. However, waning immunity, non-human reservoirs, rapid viral evolution rates, mother to infant transmission, the growing resistance to vaccination in developed countries and political instability in non-developed countries have all proven to be roadblocks to control and eradication of infectious diseases and doctors need additional therapeutic tools in their toolbox to continue to effectively fight and stave off infections.