
The laboratory of Dr Serhat Gumrukcu is located at Seraph Medical Clinic and Surgery Center, Los Angeles, California.
The Gumrukcu Lab studies gene and cell therapy particularly in the context of cancer (hematological and solid tumors), developing novel stem cell transplant methods for rare diseases, and innate molecular and cellular immunology in cancer and chronic infections like HIV/AIDS and HBV. The main objective is to develop better stem cell transplant and cell and gene therapy treatments for patients with cancer, rare genetic disorders, and infectious diseases.
In his past research, Dr Gumrukcu has developed a gene-modified autologous bone marrow transplant method that has a potential to facilitate increased engraftment in a non-myeloablative model. He has demonstrated the successful homing, engraftment and increased reconstitution capabilities of the modified bone marrow cells. The Gumrukcu Lab now focuses on creating disease-specific gene therapy vectors to harness the potential of this method. This has promising clinical use potential as an outpatient procedure in treating tens of different genetic disorders, as well as many cancers and HIV.
The current research in our laboratory focuses on studies to:
SARS-CoV-2
Cancer
HIV/AIDS
Infectious Diseases
Gene Therapy for Rare Genetic Disorders
Immune Dysregulation & Autoimmunity
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